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Marc Michelon



Joined: 20 Aug 2020
Posts: 24

PostPosted: Sun 8 Nov - 17:56 (2020)    Post subject: RE

Bonjour, voici un qcm du tutorat :
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text-indent:-14.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l4 {mso-list-id:2064019684; mso-list-type:hybrid; mso-list-template-ids:1650479902 815927442 -121983848 -435653272 -1660671568 -1904189108 77349906 -892951564 982139138 997625020;} @list l4:level1 {mso-level-number-format:alpha-upper; mso-level-tab-stop:none; mso-level-number-position:left; margin-left:35.45pt; text-indent:-18.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; 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mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l4:level4 {mso-level-tab-stop:none; mso-level-number-position:left; margin-left:143.45pt; text-indent:-18.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l4:level5 {mso-level-number-format:alpha-lower; mso-level-tab-stop:none; mso-level-number-position:left; margin-left:179.45pt; text-indent:-18.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l4:level6 {mso-level-number-format:roman-lower; mso-level-tab-stop:none; mso-level-number-position:left; margin-left:215.45pt; text-indent:-14.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l4:level7 {mso-level-tab-stop:none; mso-level-number-position:left; margin-left:251.45pt; text-indent:-18.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l4:level8 {mso-level-number-format:alpha-lower; mso-level-tab-stop:none; mso-level-number-position:left; margin-left:287.45pt; text-indent:-18.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l4:level9 {mso-level-number-format:roman-lower; mso-level-tab-stop:none; mso-level-number-position:left; margin-left:323.45pt; text-indent:-14.0pt; mso-hansi-font-family:"Arial Unicode MS"; font-variant:normal !important; text-transform:none; position:relative; top:0pt; mso-text-raise:0pt; letter-spacing:0pt; background:windowtext; mso-highlight:windowtext; mso-font-width:100%; mso-font-kerning:0pt; text-effect:none; text-effect:none; text-effect:none; text-decoration:none; text-line-through:none; vertical-align:baseline;} @list l1:level1 lfo2 {mso-level-start-at:11;} -->
11.   À propos de la traduction de protéines dans le RE :
A.     Les protéines luminales possédaient un peptide signal Cterminal
B.     Si le peptide signal est interne, l’extrémité Cterminale va forcément être dans la lumière.
C.     L’orientation de la protéine par le translocon dépend de la charge des acides aminés adjacents au domaine transmembranaire.
D.     Une séquence stoptransfert permet l’ouverture du translocon, et donc la diffusion de la protéine dans la membrane. 
E.     Les protéines dont le peptide signal se trouve à l’extrémité Cter n’utilisent pas de translocon. 
F.     Toutes les propositions précédentes sont inexactes.
Réponse : CDE
A.    FAUX, N ter
B.    FAUX, peut aussi aller dans le cytosol (dépend des protéines)
C.    VRAI
D.    VRAI
E.     VRAI, la synthèse est terminée avant l’adressage (c’est le cas des protéines Snare)
F.     FAUX


Pour la E, je suis pas d'accord car en C-ter, on utilise un canal de translocation donc un autre type de translocon, nan ?


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Publicité






PostPosted: Sun 8 Nov - 17:56 (2020)    Post subject: Publicité

PublicitéSupprimer les publicités ?
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Victor Lemaire
Conférencier


Joined: 07 Jul 2020
Posts: 24

PostPosted: Tue 10 Nov - 14:49 (2020)    Post subject: RE

Salut Marc ! 


C'est vrai que c'est assez ambiguë comme item, j'ai fait des recherches sur le translocon et en fait c'est un nom particulier qu'on donne à ce canal de translocation car il contient la Sec61. En tout cas il le précise pas dans son cours : "reconnaissance d'une séquence signal par une autre molécule que SRP qui adresse la protéine à un canal de translocation autre que Sec61 de la membrane du RE" (je t'ai remis le schéma).  


Bon courage  Okay




_________________
Victor LEMAIRE
Conférencier en Biologie Cellulaire
2020 - 2021


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Marc Michelon



Joined: 20 Aug 2020
Posts: 24

PostPosted: Tue 10 Nov - 22:53 (2020)    Post subject: RE

merci bien

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